Pharmaceutical Inorganic Chemistry Study Material

 

Pharmaceutical Inorganic Chemistry (Unit-1) Study material

UNIT I 

• Impurities in pharmaceutical substances: History of Pharmacopoeia, Sources and types of impurities, principle involved in the limit test for Chloride, Sulphate, Iron, Arsenic, Lead and Heavy metals, modified limit test for Chloride and Sulphate 
• General methods of preparation, assay for the compounds superscripted with asterisk (*), properties and medicinal uses of inorganic compounds belonging to the following classes 

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Pharmaceutical Inorganic Chemistry (Unit-2) Study material

UNIT II

• Acids, Bases and Buffers: Buffer equations and buffer capacity in general, buffers in pharmaceutical systems, preparation, stability, buffered isotonic solutions, measurements of tonicity, calculations and methods of adjusting isotonicity. 
• Major extra and intracellular electrolytes: Functions of major physiological ions, Electrolytes used in the replacement therapy: Sodium chloride*, Potassium chloride, Calcium gluconate* and Oral Rehydration Salt (ORS), Physiological acid base balance. 
• Dental products: Dentifrices, role of fluoride in the treatment of dental caries, Desensitizing agents, Calcium carbonate, Sodium fluoride, and Zinc eugenol cement. 

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Pharmaceutical Inorganic Chemistry (Unit-3) Study material

UNIT III 

• Gastrointestinal agents 
• Acidifiers: Ammonium chloride* and Dil. HCl 
• Antacid: Ideal properties of antacids, combinations of antacids, Sodium Bicarbonate*, Aluminum hydroxide gel, Magnesium hydroxide mixture 
• Cathartics: Magnesium sulphate, Sodium orthophosphate, Kaolin and Bentonite Antimicrobials: Mechanism, classification, Potassium permanganate, Boric acid, Hydrogen peroxide*, Chlorinated lime*, Iodine and its preparations 

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Pharmaceutical Inorganic Chemistry (Unit-4) Study material

UNIT IV

• Miscellaneous compounds 
• Expectorants: Potassium iodide, Ammonium chloride*. 
• Emetics: Copper sulphate*, Sodium potassium tartarate 
• Haematinics: Ferrous sulphate*, Ferrous gluconate 
• Poison and Antidote: Sodium thiosulphate*, Activated charcoal, Sodium nitrite333 
• Astringents: Zinc Sulphate, Potash Alum 

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Pharmaceutical Inorganic Chemistry (Unit-5) Study material

UNIT V

• Radiopharmaceuticals: Radio activity, Measurement of radioactivity, Properties of α, β, γ radiations, Half life, radio isotopes and study of radio isotopes - Sodium iodide I131 , Storage conditions, precautions & pharmaceutical application of radioactive substances.

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